PepAxiom

GLP-1 / metabolic

Survodutide

In clinical trials

BI 456906 · GLP-1/glucagon dual agonist

Dual GLP-1/glucagon agonist targeting MASH and obesity.

Half-life
~6.5-7 days (weekly)
Route
Subcutaneous weekly
Evidence
In clinical trials — Phase 3 (SYNCHRONIZE); FDA Breakthrough Therapy for MASH. Not approved.

What it is

An investigational once-weekly peptide co-agonizing GLP-1 and glucagon receptors, led by a focus on metabolic liver disease.

How it works

GLP-1 agonism curbs appetite and glycemia while glucagon activation raises energy expenditure and hepatic lipid metabolism.

Studied for

MASH/liver fibrosis, obesity, T2D.

Regulatory status

Investigational; not approved.

Safety

GI effects common, managed by titration; long-term liver/CV outcomes under study.

From the PeptideLab community · real discussions
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What the community reports about Survodutide

Aggregated from real community discussions across social platforms and forums. Anecdotal and self-reported — not causal, not medical advice.

The Boehringer Ingelheim GLP-1/Glucagon dual agonist (BI 456906) — Phase 3 development for obesity, T2D, and NASH/MASH (liver). Mechanism similar to Mazdutide; no FDA approval yet; corpus has no user-experience data.

9
discussions analyzed
Multi-source
social + forums
Weight / fat loss
most-discussed topic
What people discuss
Weight / fat loss55.6%
Strength / muscle33.3%
Bloodwork / labs22.2%
Energy / fatigue11.1%
Recovery / healing11.1%
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Typical reported dose ranges, cycle structures, warnings, and the complete community insight set — rolling out in the Pro app.

Aggregated from public discussions and community forums, synthesized into themes and counts. Anecdotal and self-reported — not causal, not evidence a compound is safe or effective, not medical advice, and not a recommendation to use. No dosing shown.

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Educational information only — not medical advice, and not a recommendation to use any compound. Many peptides here are not approved for human use; legal status and evidence quality vary and are noted above. This page contains no dosing information. Consult a qualified clinician before making any health decision.