Cosmetic / skin
Argireline
Cosmetic (topical)Acetyl Hexapeptide-8 · Cosmetic neuropeptide
Popular topical 'Botox-in-a-jar' wrinkle peptide.
What it is
A synthetic hexapeptide patterned on SNAP-25, one of the most widely used cosmetic anti-aging peptides.
How it works
Competitively inhibits SNARE-complex formation to reduce neurotransmitter release and expression-line micro-contractions.
Studied for
Expression wrinkles (forehead, crow's feet).
Regulatory status
Cosmetic ingredient (not a drug); OTC skincare.
Safety
Well tolerated; occasional mild irritation; realistic (modest) expectations warranted.
Educational information only — not medical advice, and not a recommendation to use any compound. Many peptides here are not approved for human use; legal status and evidence quality vary and are noted above. This page contains no dosing information. Consult a qualified clinician before making any health decision.